Product Information

4-Fluorobenzylamine <br>CAS NO. 140-75-0 is liquid at room temperature. The density is 1.102g/mL, 20/4℃. The refractive index is 1.512nD20. The flash point is 66°C. The boiling point is 182-183°C. The auto-ignition point or ignition temperature is 67°C. It is stable under normal temperature and pressure. As an intermediate of antiallergic drug Astemizole, analgesic Flupirine, it is often used as intermediate of medicine and pesticide.

Resolve Resolution

In a 100ml reaction flask, add 25.5g (0.1mol) of N-(4-fluorobenzyl)phthalimide and 25ml of absolute ethanol, then add 6.3g (0.1mol) of 80% hydrazine hydrate solution, heat Reflux 0.5g. Excessive hydrochloric acid was added to decompose the precipitated white precipitate, after cooling, an appropriate amount of water was added to stir, and suction filtered. The filtrate was neutralized with NaOH solution and extracted with ether. The ether extract was dried and then evaporated to remove ether, and then distilled under reduced pressure to collect fractions at 44-46°C (67kPa) to obtain 7.1 g of p-fluorobenzylamine with a yield of 56.5%.

Specifications：

CAS NO. 140-75-0

Appearance: Colorless clear liquid

Purity : 99%min

Boiling point: 183ºC

Refractive Index: 1.5117

Packing: 50kg or 200kg net steel drum lined with plastics

Storage Condition: Stable under normal temperatures and pressures. Keep away from heat, sparks, and flame. Keep away from sources of ignition. Keep container closed when not in use. Store in a tightly closed container. Store in a cool, dry, well-ventilated area away from incompatible substances. Corrosives area.

A benzylamine derivative as a potassium channel blocking agent.

Safety Info：